Achaogen (NASDAQ: AKAO) and Nexvet Biopharma (NASDAQ:NVET) are both small-cap medical companies, but which is the better business? We will compare the two businesses based on the strength of their valuation, risk, analyst recommendations, earnings, dividends, institutional ownership and profitability.

Analyst Ratings

This is a summary of recent ratings for Achaogen and Nexvet Biopharma, as reported by

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Achaogen 0 1 8 0 2.89
Nexvet Biopharma 0 1 0 0 2.00

Achaogen presently has a consensus target price of $25.63, indicating a potential upside of 137.71%. Nexvet Biopharma has a consensus target price of $6.72, indicating a potential upside of 0.00%. Given Achaogen’s stronger consensus rating and higher probable upside, analysts clearly believe Achaogen is more favorable than Nexvet Biopharma.

Earnings and Valuation

This table compares Achaogen and Nexvet Biopharma’s revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Achaogen $41.77 million 10.94 -$71.22 million ($3.60) -2.99
Nexvet Biopharma N/A N/A N/A ($1.75) -3.84

Nexvet Biopharma has lower revenue, but higher earnings than Achaogen. Nexvet Biopharma is trading at a lower price-to-earnings ratio than Achaogen, indicating that it is currently the more affordable of the two stocks.


This table compares Achaogen and Nexvet Biopharma’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Achaogen -593.61% -80.44% -51.17%
Nexvet Biopharma N/A -102.72% -89.82%

Institutional & Insider Ownership

85.7% of Achaogen shares are owned by institutional investors. Comparatively, 48.4% of Nexvet Biopharma shares are owned by institutional investors. 8.4% of Achaogen shares are owned by insiders. Comparatively, 37.0% of Nexvet Biopharma shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.


Achaogen beats Nexvet Biopharma on 7 of the 10 factors compared between the two stocks.

About Achaogen

Achaogen, Inc. is a late-stage biopharmaceutical company. The Company is engaged in the discovery, development and commercialization of antibacterial treatments against multi-drug resistant (MDR) gram-negative infections. The Company is involved in researching and developing plazomicin, its lead product candidate, for the treatment of serious bacterial infections, including complicated urinary tract infection (cUTI), blood stream infections and other infections due to MDR Enterobacteriaceae, including carbapenem-resistant Enterobacteriaceae (CRE). Plazomicin is an intravenous aminoglycoside antibiotic. The Company has developed plazomicin by chemically modifying sisomicin, a naturally occurring aminoglycoside, in order to overcome common aminoglycoside resistance mechanisms. The Company has a portfolio of small molecule and antibody programs. The Company’s Early Development programs include C-Scape and LpxC.

About Nexvet Biopharma

Nexvet Biopharma public limited company is a clinical-stage biopharmaceutical company focused on transforming the therapeutic market for companion animals by developing and commercializing species-specific biologics. The Company’s platform technology, which it refers to as PETization, is an algorithmic approach that enables the Company to create monoclonal antibodies (mAbs) a type of biologic, that are designed to be recognized as self or native by an animal’s immune system, a property referred to as 100% species-specificity. PETization is designed to build upon the safety and efficacy data from clinically tested human therapies to create new therapies for companion animals. Biologics generally include mAbs, which are targeted antibodies derived from identical (clonal) cells. The Company’s advanced product candidates are in pivotal-phase development: ranevetmab (or NV-01) and frunevetmab (or NV-02).

Receive News & Ratings for Achaogen Daily - Enter your email address below to receive a concise daily summary of the latest news and analysts' ratings for Achaogen and related companies with's FREE daily email newsletter.