OptiNose (NASDAQ: OPTN) and Albany Molecular Research (NASDAQ:AMRI) are both small-cap healthcare companies, but which is the better investment? We will compare the two businesses based on the strength of their risk, valuation, institutional ownership, analyst recommendations, dividends, earnings and profitability.

Valuation & Earnings

This table compares OptiNose and Albany Molecular Research’s gross revenue, earnings per share (EPS) and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
OptiNose N/A N/A N/A ($4.96) -3.27
Albany Molecular Research N/A N/A N/A ($1.43) -15.20

Albany Molecular Research is trading at a lower price-to-earnings ratio than OptiNose, indicating that it is currently the more affordable of the two stocks.


This table compares OptiNose and Albany Molecular Research’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
OptiNose N/A N/A N/A
Albany Molecular Research -5.93% -13.39% -3.42%

Analyst Ratings

This is a breakdown of recent ratings for OptiNose and Albany Molecular Research, as provided by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
OptiNose 0 0 4 0 3.00
Albany Molecular Research 0 4 0 0 2.00

OptiNose currently has a consensus price target of $29.25, suggesting a potential upside of 80.44%. Albany Molecular Research has a consensus price target of $18.00, suggesting a potential downside of 17.20%. Given OptiNose’s stronger consensus rating and higher possible upside, analysts plainly believe OptiNose is more favorable than Albany Molecular Research.

Institutional and Insider Ownership

2.0% of OptiNose shares are held by institutional investors. Comparatively, 72.1% of Albany Molecular Research shares are held by institutional investors. 14.5% of Albany Molecular Research shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.


OptiNose beats Albany Molecular Research on 7 of the 10 factors compared between the two stocks.

OptiNose Company Profile

OptiNose, Inc. is a pharmaceutical company. The Company is focused on the development and commercialization of products for patients treated by ear, nose and throat, or ENT, and allergy specialists. The Company’s products candidates include XHANCE (Nasal Polyps), XHANCE (Chornic Sinusitis) OPN-300, OPN-021, and other. The Company’s lead product, XHANCE (fluticasone propionate) nasal spray, utilizes breath powered exhalation delivery system (EDS), to deliver a topically acting and potent anti-inflammatory corticosteroid for the treatment of chronic rhinosinusitis with nasal polyps. XHANCE has a differentiated clinical profile with the potential to become part of the standard of care for this disease because it is able to deliver medication to the primary site of inflammation.

Albany Molecular Research Company Profile

Albany Molecular Research, Inc. is a contract research and manufacturing company. The Company operates through Discovery and Development Services (DDS), Active Pharmaceutical Ingredients (API), Drug Product (DP) and Fine Chemicals (FC) segments. The DDS segment includes activities, such as drug lead discovery, optimization, drug development and small scale commercial manufacturing. The API segment includes pilot to commercial scale manufacturing of active pharmaceutical ingredients and intermediates. The DP segment includes pre-formulation, formulation and process development through commercial scale production of complex liquid-filled and lyophilized sterile injectable products and ophthalmic formulations. The FC segment includes lab to commercial scale synthesis of reagents and diverse compounds. It supplies a range of services and technologies supporting the discovery and development of pharmaceutical products, the manufacturing of API and drug product for new and generic drugs.

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